Atreza

Pronunciation: AT-row-peen
Generic Name: Atropine
Brand Name: Atreza and Sal-Tropine

Atreza is used for:

Treating spasms in the stomach, intestines, and other organs. It may also be used to decrease the production of saliva and secretions of the airway or for other conditions as determined by your doctor.

Atreza is an anticholinergic. It works by blocking the effects of a chemical in the body (acetylcholine) in the nervous system, stomach, intestines, certain glands (eg, salivary gland), urinary tract, and other tissues.

Do NOT use Atreza if:

• you are allergic to any ingredient in Atreza


• you have adhesions between the iris and lens of the eyes, asthma, blocking of the stomach or bowel, ulcerative colitis, bleeding, angle-closure glaucoma, myasthenia gravis, difficulty urinating due to a blockage, excess acid in the stomach or throat, esophagus problems (difficulty swallowing), or bowel muscle weakness

Contact your doctor or health care provider right away if any of these apply to you.

Before using Atreza:

Some medical conditions may interact with Atreza. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of megacolon or a predisposition to angle-closure glaucoma


• if you have numbness due to nerve damage, prostate problems (enlarged prostate), blockage of the bladder, trouble urinating, heart problems (congestive heart failure), hiatal hernia, or open-angle glaucoma

Some MEDICINES MAY INTERACT with Atreza. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Antihistamines (eg, diphenhydramine), medicine for Parkinson disease (eg, benztropine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Atreza's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Atreza may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Atreza:

Use Atreza as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Atreza by mouth with or without food.


• If you miss a dose of Atreza, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Atreza.

Important safety information:

• If your symptoms do not get better within a few days or if they get worse, check with your doctor.


• Atreza may cause drowsiness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Atreza with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Atreza; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.


• Do not become overheated in hot weather or while you are being active; heatstroke may occur.


• Report any symptoms of fluid or electrolyte loss to your doctor: dry mouth; thirst; weakness; lethargy; drowsiness; restlessness; muscle pain or cramps; muscle weakness; low blood pressure; infrequent urination; rapid heartbeat; stomach disorders such as nausea and vomiting.


• Atreza may make your eyes more sensitive to sunlight. It may help to wear sunglasses.


• Tell your doctor or dentist that you take Atreza before you receive any medical or dental care, emergency care, or surgery.


• Use Atreza with caution in the ELDERLY; they may be more sensitive to its effects.


• Atreza should be used with extreme caution in CHILDREN younger than 13 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Atreza while you are pregnant. It is not known if Atreza is found in breast milk. If you are or will be breast-feeding while you use Atreza, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Atreza:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; constipation; decreased salivation; decreased sweating; difficulty sleeping; difficulty swallowing; dilation of the pupils; dizziness; drowsiness; excitement; fever; headache; hot, flushed, dry skin; loss of taste; mild to severe dryness of the nose and mouth; nausea; nervousness; thirst.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in heartbeat; confusion; delirium; diarrhea; difficulty focusing your eyes; difficulty urinating; fast/irregular heartbeat; hallucinations; rash; restlessness with weakness; speech disturbance; unusual weakness; vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Atreza side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include anxiety; coma; difficulty breathing; dilated pupils; disorientation; hallucinations; high blood pressure; high body temperature; hyperactivity; muscle weakness; restlessness; seizures; severe dizziness; urinary retention; vomiting.

Proper storage of Atreza:

Store Atreza at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Atreza out of the reach of children and away from pets.

General information:

• If you have any questions about Atreza, please talk with your doctor, pharmacist, or other health care provider.


• Atreza is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Atreza. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Atreza resources

• Atreza Side Effects (in more detail)
• Atreza Use in Pregnancy & Breastfeeding
• Atreza Drug Interactions
• Atreza Support Group
• 0 Reviews for Atreza - Add your own review/rating

• Atreza Concise Consumer Information (Cerner Multum)


• Atropine Prescribing Information (FDA)


• Atropine Monograph (AHFS DI)


• Atropine Professional Patient Advice (Wolters Kluwer)


• Atropine Advanced Consumer (Micromedex) - Includes Dosage Information


• AtroPen Prescribing Information (FDA)

Compare Atreza with other medications

• Anticholinesterase Poisoning
• AV Heart Block
• Bradyarrhythmia

Antipyrine/Benzocaine/Zinc Drops

Pronunciation: an-tee-PYE-reen/BEN-zoe-kane/zink
Generic Name: Antipyrine/Benzocaine/Zinc
Brand Name: Neotic

Antipyrine/Benzocaine/Zinc Drops are used for:

Relieving pain and inflammation in the ear caused by certain ear problems. It may be used with antibiotics to treat middle ear infections. It may also be used to help remove a buildup of earwax.

Antipyrine/Benzocaine/Zinc Drops are an analgesic, anesthetic, and skin protectant combination. It works by relieving pressure; reducing inflammation, congestion, pain, and discomfort; and protecting the skin of the ear.

Do NOT use Antipyrine/Benzocaine/Zinc Drops if:

• you are allergic to any ingredient in Antipyrine/Benzocaine/Zinc Drops or to similar medicines


• you have a discharge from the ear or your eardrum is perforated

Contact your doctor or health care provider right away if any of these apply to you.

Before using Antipyrine/Benzocaine/Zinc Drops:

Some medical conditions may interact with Antipyrine/Benzocaine/Zinc Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Antipyrine/Benzocaine/Zinc Drops. However, no specific interactions with Antipyrine/Benzocaine/Zinc Drops are known at this time.

Ask your health care provider if Antipyrine/Benzocaine/Zinc Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Antipyrine/Benzocaine/Zinc Drops:

Use Antipyrine/Benzocaine/Zinc Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• For topical use in the ear canal only. Do not get Antipyrine/Benzocaine/Zinc Drops in the eyes, nose, or mouth. If you get Antipyrine/Benzocaine/Zinc Drops in your eyes, rinse right away with cool water.


• Before using, hold the ear drop container in your hand for a few minutes to warm it to body temperature.


• To use ear drops, lie down or tilt your head so that the affected ear faces up. For adults, gently pull the earlobe up and back to straighten the ear canal. For children, gently pull the earlobe down and back to straighten the ear canal. Drop the medicine into the ear canal. Keep the ear facing up for several minutes so the medicine can run to the bottom of the ear canal. A clean cotton plug may be gently inserted into the ear canal to prevent medicine from leaking out. If you are using Antipyrine/Benzocaine/Zinc Drops for ear wax removal, moisten the cotton with Antipyrine/Benzocaine/Zinc Drops before inserting it into the ear.


• To prevent germs from getting into your medicine, do not touch the applicator to any surface, including the ear. Do not rinse dropper after use. Keep the container tightly closed.


• If Antipyrine/Benzocaine/Zinc Drops are brown or contains particles, do not use it.


• If you miss a dose of Antipyrine/Benzocaine/Zinc Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Antipyrine/Benzocaine/Zinc Drops.

Important safety information:

• Antipyrine/Benzocaine/Zinc Drops may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Antipyrine/Benzocaine/Zinc Drops while you are pregnant. It is not known if Antipyrine/Benzocaine/Zinc Drops are found in breast milk. If you are or will be breast-feeding while you use Antipyrine/Benzocaine/Zinc Drops, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Antipyrine/Benzocaine/Zinc Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); irritation not present when you began using Antipyrine/Benzocaine/Zinc Drops.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

See also: Antipyrine/Benzocaine/Zinc side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/), or emergency room immediately.

Proper storage of Antipyrine/Benzocaine/Zinc Drops:

Store Antipyrine/Benzocaine/Zinc Drops at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Protect from freezing. Keep the container tightly closed. Store away from heat and light. Keep Antipyrine/Benzocaine/Zinc Drops out of the reach of children and away from pets.

General information:

• If you have any questions about Antipyrine/Benzocaine/Zinc Drops, please talk with your doctor, pharmacist, or other health care provider.


• Antipyrine/Benzocaine/Zinc Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Antipyrine/Benzocaine/Zinc Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Antipyrine/Benzocaine/Zinc resources

• Antipyrine/Benzocaine/Zinc Side Effects (in more detail)
• Antipyrine/Benzocaine/Zinc Use in Pregnancy & Breastfeeding
• Antipyrine/Benzocaine/Zinc Support Group
• 0 Reviews · Be the first to review/rate this drug

Astelin Ready-Spray

Generic Name: azelastine (Nasal route)

a-ZEL-as-teen

Commonly used brand name(s)

In the U.S.

• Astelin


• Astelin Ready-Spray


• Astepro

Available Dosage Forms:

• Spray

Therapeutic Class: Nasal Agent

Pharmacologic Class: Antihistamine

Uses For Astelin Ready-Spray

Azelastine nasal spray is used to help relieve symptoms (e.g., stuffy or runny nose, itching, sneezing) of seasonal (short-term) or perennial (year-round) allergic rhinitis (hay fever), and vasomotor rhinitis.

This medicine works by preventing certain cells to release substances that cause the allergic reaction.

This medicine is available only with your doctor's prescription.

Before Using Astelin Ready-Spray

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of azelastine in children below 12 years of age. Safety and efficacy have not been established.

Geriatric

Although appropriate studies on the relationship of age to the effects of azelastine have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution in patients receiving azelastine.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Cimetidine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Kidney disease—Blood levels of azelastine may be increased, leading to increased effects.

Proper Use of azelastine

This section provides information on the proper use of a number of products that contain azelastine. It may not be specific to Astelin Ready-Spray. Please read with care.

Use this medicine only as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered. To do so may increase the chance of side effects.

This medicine usually comes with patient information insert. Read and follow the instructions carefully. Ask your doctor if you have any questions.

This medicine is for use only in the nose. Do not get any of it in your eyes or on your mouth. If it does get on these areas, rinse it off right away.

Before using this medicine, gently blow your nose to clear the nostrils.

To prepare this medicine:

• Before you use a new bottle of azelastine spray, the spray pump will need to be primed (started). If your pharmacist assembled the unit for you, check to see if it has already been primed by pumping the unit once. If a full spray comes out, the unit has already been primed; if not you must prime the pump.


• To prime a new bottle, hold the bottle upright and away from you, then pump it six times or until you see a fine spray.


• If you have not used the spray for 3 or more days, pump it two times or until you see a fine spray.

To keep the applicator clean, wipe the nosepiece with a clean tissue and replace the dust cap after each use.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For nasal dosage form (spray):
  
  • For symptoms of seasonal allergic rhinitis:
    
    • Adults, teenagers, and children 12 years of age and older—1 or 2 sprays in each nostril two times a day, or 2 sprays in each nostril once a day.
    
    
    • Children up to 12 years of age—Use and dose must be determined by your doctor.
    
    
  
  
  • For symptoms of perennial allergic rhinitis:
    
    • Adults, teenagers, and children 12 years of age and older—2 sprays in each nostril two times a day.
    
    
    • Children up to 12 years of age—Use and dose must be determined by your doctor.
    
    
  
  
  • For treatment of vasomotor rhinitis:
    
    • Adults and teenagers—Use 2 sprays in each nostril two times a day.
    
    
    • Children younger than 12 years of age—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the bottle upright with the pump tightly closed.

Precautions While Using Astelin Ready-Spray

Your doctor should check you or your child at regular visits for any problems or unwanted effects that may be caused by this medicine.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that makes you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using this medicine.

This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally. Even if used at bedtime, it may cause some people to feel drowsy or less alert on arising. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.

Keep the spray away from the eyes because this medicine may cause irritation or blurred vision. Closing your eyes while you are using this medicine may help keep it out of your eyes.

If your symptoms do not improve within a few days or if they become worse, check with your doctor.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Astelin Ready-Spray Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

• Blood in the urine


• cough


• eye pain, eye redness, blurred vision or other change in vision


• rapid heartbeat


• shortness of breath, tightness in the chest, troubled breathing, or wheezing


• skin rash, hives, or itching


• sores in the mouth or on the lips

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Bitter taste in the mouth


• drowsiness or sleepiness

Less common

• Bloody mucus or unexplained nosebleeds


• burning inside the nose


• dizziness


• dryness of the mouth


• headache


• muscle aches or pain


• nausea


• sore throat


• sudden outbursts of sneezing


• unusual tiredness or weakness


• weight gain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Astelin Ready-Spray side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Astelin Ready-Spray resources

• Astelin Ready-Spray Side Effects (in more detail)
• Astelin Ready-Spray Use in Pregnancy & Breastfeeding
• Astelin Ready-Spray Drug Interactions
• Astelin Ready-Spray Support Group
• 7 Reviews for Astelin Ready-Spray - Add your own review/rating

Compare Astelin Ready-Spray with other medications

• Hay Fever

Antipyrine/Benzocaine/Phenylephrine

Pronunciation: an-tee-PYE-reen/BEN-zoe-kane/fen-ill-EF-rin
Generic Name: Antipyrine/Benzocaine/Phenylephrine
Brand Name: Examples include Otogesic and Tympagesic

Antipyrine/Benzocaine/Phenylephrine is used for:

Relieving pain in the ear caused by various conditions. It may be used with antibiotics given by mouth to treat middle ear infections.

Antipyrine/Benzocaine/Phenylephrine is an analgesic, anesthetic, and sympathomimetic combination. It works by relieving pressure and reducing inflammation, congestion, pain, and discomfort.

Do NOT use Antipyrine/Benzocaine/Phenylephrine if:

• you are allergic to any ingredient in Antipyrine/Benzocaine/Phenylephrine or to similar medicines


• your eardrum is perforated or you have discharge from your ear

Contact your doctor or health care provider right away if any of these apply to you.

Before using Antipyrine/Benzocaine/Phenylephrine:

Some medical conditions may interact with Antipyrine/Benzocaine/Phenylephrine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you are allergic to other local anesthetics (eg, lidocaine)


• if you have asthma, high blood pressure, glaucoma or increased eye pressure, diabetes, heart problems (eg, ischemic heart disease), an enlarged prostate, or an overactive thyroid

Some MEDICINES MAY INTERACT with Antipyrine/Benzocaine/Phenylephrine. However, no specific interactions with Antipyrine/Benzocaine/Phenylephrine are known at this time.

Ask your health care provider if Antipyrine/Benzocaine/Phenylephrine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Antipyrine/Benzocaine/Phenylephrine:

Use Antipyrine/Benzocaine/Phenylephrine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• For topical use in the ear canal only. Do not get Antipyrine/Benzocaine/Phenylephrine in the eyes, nose, or mouth. If you get Antipyrine/Benzocaine/Phenylephrine in your eyes, rinse thoroughly with cool water.


• To use ear drops, lie down or tilt your head so that the affected ear faces up. For adults, gently pull the earlobe up and back to straighten the ear canal. For children, gently pull the earlobe down and back to straighten the ear canal. Drop the medicine into the ear canal. Keep the ear facing up for several minutes so the medicine can run to the bottom of the ear canal. Moisten a clean cotton plug with Antipyrine/Benzocaine/Phenylephrine and gently insert into the ear canal to prevent medicine from leaking out.


• To prevent germs from contaminating the medicine, do not touch the applicator to any surface, including the ear. Do not rinse dropper after use. Keep the container tightly closed.


• If you miss a dose of Antipyrine/Benzocaine/Phenylephrine, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Antipyrine/Benzocaine/Phenylephrine.

Important safety information:

• Some of these products contain sulfites. Sulfites may cause an allergic reaction in some patients (eg, asthma patients). If you have ever had an allergic reaction to sulfites, ask your pharmacist if your product has sulfites in it.


• Antipyrine/Benzocaine/Phenylephrine may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.


• Use Antipyrine/Benzocaine/Phenylephrine with caution in the ELDERLY; they may be more sensitive to its effects


• Antipyrine/Benzocaine/Phenylephrine should be used with extreme caution in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Antipyrine/Benzocaine/Phenylephrine while you are pregnant. It is not known if Antipyrine/Benzocaine/Phenylephrine is found in breast milk. If you are or will be breast-feeding while you use Antipyrine/Benzocaine/Phenylephrine, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Antipyrine/Benzocaine/Phenylephrine:

All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); irritation not present when you began using Antipyrine/Benzocaine/Phenylephrine; redness, itching, blistering, or oozing at the application site.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Antipyrine/Benzocaine/Phenylephrine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include anxiety; dizziness; headache; nausea; nervousness; ringing in the ears; sweating; unusually pale or cool skin; vomiting.

Proper storage of Antipyrine/Benzocaine/Phenylephrine:

Store Antipyrine/Benzocaine/Phenylephrine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Protect from freezing. Keep the container tightly closed. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Antipyrine/Benzocaine/Phenylephrine out of the reach of children and away from pets.

General information:

• If you have any questions about Antipyrine/Benzocaine/Phenylephrine, please talk with your doctor, pharmacist, or other health care provider.


• Antipyrine/Benzocaine/Phenylephrine is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Antipyrine/Benzocaine/Phenylephrine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Antipyrine/Benzocaine/Phenylephrine resources

• Antipyrine/Benzocaine/Phenylephrine Side Effects (in more detail)
• Antipyrine/Benzocaine/Phenylephrine Use in Pregnancy & Breastfeeding
• Antipyrine/Benzocaine/Phenylephrine Drug Interactions
• Antipyrine/Benzocaine/Phenylephrine Support Group
• 0 Reviews for Antipyrine/Benzocaine/Phenylephrine - Add your own review/rating

Compare Antipyrine/Benzocaine/Phenylephrine with other medications

• Otitis Media

Hemo-Stat Solution

Dosage Form: dental solution
TOPICAL

HEMO-STAT

SOLUTION

DIRECTIONS

Soak a cotton-tipped applicator or a pledget of cotton with Hemo-Stat. Apply to bleeding area with pressure until hemorrhage is arrested.

Note

Should a small dark coagulum appear, flush it away with water. This will have no effect on the hemostatic action.

Hemo-Stat Solution contains 25% Aluminum Chloride in an aqueous vehicle. It contains no epinephrine.

CAUTION

Federal (U.S.A.) Law prohibits dispensing without a prescription.

Made in USA

PRINCIPAL DISPLAY PANEL - 30 ml Bottle Label

HENRY SCHEIN®

TOPICAL Hemo-Stat Solution

REF 100-2645

Contains: 25% Aluminum Chloride in an aqueous vehicle.

For Professional Use Only

Warning: Corrosive Consult MSDS

Distributed by:

HENRY SCHEIN INC.

Melville, NY 11747 USA

Henry Schein U.K. Holdings Ltd.

Gillingham ME 8 0SB U.K.

1 FL. OZ. (30 ml)

MADE IN USA

TOPICAL HEMO-STAT  aluminum chloride  solution

Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 0404-1080 Route of Administration DENTAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength Aluminum Chloride (Aluminum) Aluminum Chloride 250 mg  in 1 g

Inactive Ingredients Ingredient Name Strength Water

Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 0404-1080-01 30 g In 1 BOTTLE, GLASS None 2 0404-1080-02 15 g In 1 BOTTLE, GLASS None

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
UNAPPROVED DRUG OTHER		02/19/1963

Labeler - Henry Schein (012430880)

Registrant - DSHealthcare (056296981)

Establishment
Name	Address	ID/FEI	Operations
DENTSPLY Caulk		083235549	MANUFACTURE

Revised: 05/2010Henry Schein

Acuvail

Generic Name: ketorolac ophthalmic (KEE toe ROLE ak)

Brand Names: Acular, Acular LS, Acular PF, Acuvail

What is ketorolac ophthalmic?

Ketorolac is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Ketorolac works by reducing hormones that cause inflammation and pain in the body.

Ketorolac ophthalmic (for the eye) is used to relieve eye itching caused by seasonal allergies.

Ketorolac ophthalmic is also used to reduce swelling, pain, and burning or stinging after cataract surgery or corneal refractive surgery.

Ketorolac ophthalmic may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about ketorolac ophthalmic?

You should not use this medication if you are allergic to ketorolac or other NSAIDs (nonsteroidal anti-inflammatory drugs).

Before using ketorolac ophthalmic, tell your doctor if you are allergic to any medications, or if you have a bleeding or blood-clotting disorder, diabetes, arthritis, glaucoma, dry eye syndrome, or if you have had other recent eye surgeries.

Tell your doctor about all other medications you use, especially a blood thinner such as warfarin (Coumadin).

Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label. Using the medication for longer than prescribed may increase the risk of serious side effects on your eyes.

While you are using this medication, do not wear any contact lens that has not been approved by your doctor. Do not use any other eye medications unless your doctor has prescribed them.

What should I discuss with my healthcare provider before I use ketorolac ophthalmic?

You should not use this medication if you are allergic to ketorolac or other NSAIDs.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medication:

• 
  

  a bleeding or blood-clotting disorder;

  
  


• 
  

  diabetes;

  
  


• 
  

  arthritis;

  
  


• 
  

  glaucoma;

  
  


• 
  

  dry eye syndrome; or

  
  


• 
  

  if you have had other recent eye surgeries.

  
  

FDA pregnancy category C. It is not known whether ketorolac ophthalmic is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether ketorolac ophthalmic passes into breast milk or if it could harm a nursing baby. Do not use ketorolac ophthalmic without telling your doctor if you are breast-feeding a baby.

How should I use ketorolac ophthalmic?

Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Ketorolac ophthalmic is usually given 24 hours before cataract surgery, and continued for up to 14 days after surgery. Using the medication for longer than prescribed may increase the risk of serious side effects on your eyes.

Wash your hands before using the eye drops.

To apply the eye drops:

• 
  

  Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the dropper tip down. Look up and away from the dropper as you squeeze out a drop, then close your eye.

  
  


• 
  

  Gently press your finger to the inside corner of the eye (near your nose) for about 1 minute to keep the liquid from draining into your tear duct.

  
  


• 
  

  Use the eye drops only in the eye you are having surgery on.

  
  


• 
  

  Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

  
  

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your doctor for a new prescription.

Store the drops at room temperature away from heat and moisture. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of ketorolac is not likely to cause life-threatening symptoms.

What should I avoid while using ketorolac ophthalmic?

While using this medication, do not wear any contact lens that has not been approved by your doctor.

Do not use any other eye medications unless your doctor has prescribed them.

Ketorolac ophthalmic side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

• 
  

  severe burning, stinging, or itching of your eyes;

  
  


• 
  

  eye pain, redness, or watering;

  
  


• 
  

  vision changes, increased sensitivity to light;

  
  


• 
  

  white patches on your eyes; or

  
  


• 
  

  crusting or drainage from your eyes.

  
  

Less serious side effects may include:

• 
  

  mild burning, stinging, or itching of your eyes;

  
  


• 
  

  swollen or puffy eyelids; or

  
  


• 
  

  headache.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect ketorolac ophthalmic?

Tell your doctor about all other medications you use, especially a blood thinner such as warfarin (Coumadin).

This list is not complete and there may be other drugs that can interact with ketorolac ophthalmic. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

More Acuvail resources

• Acuvail Side Effects (in more detail)
• Acuvail Use in Pregnancy & Breastfeeding
• Acuvail Drug Interactions
• Acuvail Support Group
• 0 Reviews for Acuvail - Add your own review/rating

• Acuvail Consumer Overview


• Acuvail Prescribing Information (FDA)


• Acuvail Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Acuvail Advanced Consumer (Micromedex) - Includes Dosage Information


• Acular Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Acular eent Monograph (AHFS DI)


• Acular Prescribing Information (FDA)


• Acular LS Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Acular LS Prescribing Information (FDA)


• Acular PF Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Acular PF Prescribing Information (FDA)

Compare Acuvail with other medications

• Postoperative Ocular Inflammation

Where can I get more information?

• Your doctor or pharmacist can provide more information about ketorolac ophthalmic.

See also: Acuvail side effects (in more detail)

EGFR inhibitors

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Epidermal growth factor receptor (EGFR, also known as ErbB-1 or HER-1) inhibitors are either tyrosine kinase inhibitors or monoclonal antibodies that slow down or stop cell growth.

EGFRs are transmembrane receptors present on the cell membranes. They have an extracellular binding component, a transmembrane component and an intracellular tyrosine kinase component. EGFRs play an important role in controlling normal cell growth, apoptosis and other cellular functions. Mutations of EGFRs can lead to continual or abnormal activation of the receptors causing unregulated cell division, which can account for some types of cancers.

Tyrosine kinase inhibitors bind to the tyrosine kinase domain in the epidermal growth factor receptor and stop the activity of the EGFR.

Monoclonal antibodies bind to the extracellular component of the epidermal growth factor receptors, prevent the actual substrates from binding to the receptors therefore prevent activation of the epidermal growth factor receptor.

EGFR inhibitors are used to treat non-small-cell lung cancer, pancreatic cancer, breast cancer, colon cancer and some other cancers that are caused by epidermal growth factor receptor up-regulation.

See also

Medical conditions associated with EGFR inhibitors:

• Breast Cancer
• Breast Cancer, Metastatic
• Colorectal Cancer
• Head and Neck Cancer
• Non-Small Cell Lung Cancer
• Pancreatic Cancer
• Renal Cell Carcinoma
• Squamous Cell Carcinoma
• Thyroid Cancer

Drug List:

Iressa

Tarceva

Erbitux

Tykerb

Vectibix

Caprelsa