Isalgen may be available in the countries listed below.
Scopolamine butylbromide (a derivative of Scopolamine) is reported as an ingredient of Isalgen in the following countries:
International Drug Name Search
Alkeran should only be used under the supervision of a doctor experienced with the use of cancer medicines. Alkeran may cause a decrease in the body's blood cells (bone marrow suppression), which could cause bleeding problems or infection. It may also cause a certain type of blood cell cancer (leukemia) or a severe allergic reaction. Notify your doctor immediately if you develop unusual bleeding or bruising, unusual fatigue, symptoms of an allergic reaction (eg, rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue), or signs of an infection (eg, fever, chills, persistent sore throat).
Treating symptoms of a certain type of cancer (multiple myeloma). It may also be used for other conditions as determined by your doctor.
Alkeran is an alkylating agent. It works by destroying resting and rapidly dividing tumor cells in certain types of cancer.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Alkeran. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Alkeran. Tell your health care provider if you are taking any other medicines, especially any of the following:
This may not be a complete list of all interactions that may occur. Ask your health care provider if Alkeran may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Alkeran as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Alkeran.
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; hair loss; nausea; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood in urine or stools; chest pain; dark urine; dizziness or light-headedness; fainting; fast heartbeat; fatigue; fever or chills; irregular or absent menstrual periods; numbness of an arm or leg; pain, swelling, or redness at the injection site; pale stools; persistent cough; persistent loss of appetite; severe or persistent diarrhea, nausea, or vomiting; shortness of breath; sore throat; sores on the mouth, tongue, or lips; stomach pain; sudden, severe headache; swelling of the hands, ankles, or feet; unusual bruising or bleeding; unusual lumps or growths; unusual tiredness or weakness; weight loss; yellowing eyes and skin.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
See also: Alkeran side effects (in more detail)
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include decreased urination; diarrhea; paralysis; seizures; severe drowsiness; severe nausea and vomiting; sores on the mouth, tongue, or lips; symptoms of stomach or bowel bleeding (eg, black, tarry, or bloody stools; vomit that looks like coffee grounds); trouble breathing.
Alkeran is usually handled and stored by a health care provider. If you are using Alkeran at home, store Alkeran as directed by your pharmacist or health care provider. Keep Alkeran out of the reach of children and away from pets.
This information is a summary only. It does not contain all information about Alkeran. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
Generic Name: lorazepam (Injection route)
lor-AZ-e-pam
In the U.S.
Available Dosage Forms:
Therapeutic Class: Antianxiety
Pharmacologic Class: Benzodiazepine, Short or Intermediate Acting
Lorazepam injection is used before certain medical procedures, such as surgery, to relieve anxiety. When lorazepam is used before surgery, the patient will not remember some of the details about the procedure. This medicine is also used to treat certain convulsive (seizure) disorders, such as epilepsy.
Lorazepam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.
This medicine is available only with your doctor's prescription.
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of lorazepam injection in the pediatric population. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of lorazepam injection in the elderly. However, elderly patients are more likely to have severe drowsiness, or age-related heart, liver, or kidney problems, which may require an adjustment in the dose in patients receiving lorazepam injection.
| Pregnancy Category | Explanation | |
|---|---|---|
| All Trimesters | D | Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk. |
Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
A nurse or other trained health professional will give you this medicine. This medicine is given through a needle placed in one of your veins or given as a shot into one of your muscles.
It is very important that your doctor check your progress after you receive this medicine to make sure it is working properly and to check for any unwanted effects.
Using this medicine while you are pregnant can harm your unborn baby. If you think you have become pregnant, tell your doctor right away.
This medicine may cause drowsiness, trouble with thinking, trouble with controlling movements, or trouble with seeing clearly. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert or able to think or see well.
If you develop any unusual or strange thoughts and behavior while taking lorazepam injection, be sure to discuss it with your doctor. Some changes that have occurred in people taking this medicine are like those seen in people who drink too much alcohol. Other changes might be confusion, agitation, and hallucinations (seeing, hearing, or feeling things that are not there).
This medicine will add to the effects of alcohol and other central nervous system (CNS) depressants. CNS depressants are medicines that slow down the nervous system, which may cause drowsiness or make you less alert. Some examples of CNS depressants are antihistamines or medicine for hay fever, allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates (used for seizures); muscle relaxants; or anesthetics (numbing medicines), including some dental anesthetics. This effect may last for a few days after you stop taking this medicine. Check with your doctor before taking any of the above while you are using this medicine.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See also: Ativan Injection side effects (in more detail)
The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.
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Generic Name: brompheniramine and phenylephrine (BROM fen IR a meen and FEN il EFF rin)
Brand Names: Alacol, Alenaze-D, Alenaze-D NR, B-Vex D, BPM PE, Brom Tann PE, Bromfed, Bromfed-PD Capsules, BroveX ADT, BroveX PEB, Brovex-D, Children's Cold & Allergy, Dimaphen Elixir, Dimetapp Cold & Allergy, Entre-B, J-Tan D, J-Tan D SR, Phenyl 15/12mg, Phenyl 7.5/6mg, RespaHist II, Rhinabid, Rhinabid PD, Seradex-LA, Tanabid SR, V-Hist, VazoBid, VaZol-D, Vazotab, Zotex-PE
Brompheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).
The combination of brompheniramine and phenylephrine is used to treat nasal congestion, sneezing, itching, watery eyes, and runny nose caused by allergies, hay fever, and the common cold.
Brompheniramine and phenylephrine may also be used for purposes not listed in this medication guide.
Ask a doctor or pharmacist about taking brompheniramine and phenylephrine if you have heart disease or high blood pressure, diabetes, a thyroid disorder, glaucoma, kidney disease, an enlarged prostate, or problems with urination.
Ask a doctor or pharmacist if it is safe for you to take brompheniramine and phenylephrine if you have:
heart disease or high blood pressure;
diabetes;
a thyroid disorder;
glaucoma;
kidney disease;
an enlarged prostate; or
problems with urination.
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cough or cold medicine is usually taken only for a short time until your symptoms clear up.
The chewable tablet must be chewed before you swallow it.
Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).
Avoid becoming overheated or dehydrated during exercise and in hot weather.
Avoid taking this medication if you also take diet pills, caffeine pills, or other stimulants (such as ADHD medications). Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.
fast, pounding, or uneven heartbeat;
severe dizziness, anxiety, restless feeling, or nervousness;
easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms;
nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).
Less serious side effects may include:
drowsiness or dizziness;
blurred vision;
dry mouth, nose, or throat;
mild stomach pain, constipation;
problems with memory or concentration;
feeling restless or excited (especially in children);
sleep problems (insomnia); or
warmth, redness, or tingly feeling under your skin.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all other medications you are using, especially:
medicines to treat high blood pressure;
a beta blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Dutoprol, Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others; or
antidepressants such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others.
This list is not complete and other drugs may interact with brompheniramine and phenylephrine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
See also: Entre-B side effects (in more detail)
Myleran tablets 2 mg
busulfan
Myleran tablets contain a medicine called busulfan. This belongs to a group of medicines called cytotoxics (also called chemotherapy). Myleran is used for certain blood problems and cancers of the blood. It works by reducing the number of new blood cells your body makes.
Myleran is used for:
Ask your doctor if you would like more explanation about these diseases.
Do not take if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Myleran.
Before you take Myleran, tell your doctor or pharmacist if:
If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking Myleran.
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. This includes herbal medicines.
In particular tell your doctor or pharmacist if you are taking any of the following:
Do not take Myleran if you are planning to have a baby. This applies to both men and women. Myleran may harm your sperm or eggs. Reliable contraceptive precautions must be taken to avoid pregnancy whilst you or your partner are taking these tablets. Ask your doctor for advice.
If you are already pregnant, it is important to talk to your doctor before taking Myleran.
Do not breast-feed while taking Myleran. Ask your doctor or midwife for advice.
Myleran should only be given to you by a specialist doctor who is experienced in treating blood problems.
Always take Myleran exactly as your doctor has told you. It is important to take your medicine at the right times. The label on your pack will tell you how many tablets to take and how often to take them. If the label doesn't say or if you are not sure, ask your doctor, nurse or pharmacist.
The dose of Myleran depends on your blood problem or blood cancer (see section 1)
Chronic granulocytic leukaemia (also called chronic myeloid leukaemia)
Polycythaemia vera
Myelofibrosis and essential thrombocythaemia
Haematopoietic progenitor cell transplantation
If you take more Myleran than you should, tell your doctor immediately or go to a hospital straight away. Take the medicine pack with you.
Tell your doctor. Do not take a double dose to make up for a forgotten dose.
Like all medicines, Myleran can cause side effects, although not everybody gets them.
Talk to your doctor if you have any of the following side effects which may also happen with this medicine:
Very common (affects more than 1 in 10 people)
Common (affects less than 1 in 10 people)
Uncommon (affects less than 1 in 100 people)
Rare (affects less than 1 in 1,000 people)
Very rare (affects less than 1 in 10,000 people)
If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
The active ingredient is busulfan. Each Myleran tablet contains 2 mg of busulfan. The other ingredients are anhydrous lactose, pregelatinised starch, magnesium stearate, hypromellose, titanium dioxide (E171) and triacetin.
Myleran tablets are white, film-coated tablets and are marked with ‘GX EF3’ on one side and ‘M’ on the other. Your Myleran tablets are in bottles of 25 tablets.
Marketing Authorisation holder:
Manufacturer:
Other formats:
To listen to or request a copy of this leaflet in Braille, large print or audio please call, free of charge:
0800 198 5000 (UK only)
Please be ready to give the following information:
Product name: Myleran 2 mg Reference number: 00003/5112R
This is a service provided by the Royal National Institute of Blind People.
Leaflet date: September 2008
Myleran is a registered trademark of the GlaxoSmithKline group of companies
© 2008 GlaxoSmithKline group of companies
7037898-0144
Generic Name: hydrochlorothiazide and methyldopa (HYE droe KLOR oh THYE a zide and METH il DOE pa)
Brand Names: Aldoril 15, Aldoril 25, Aldoril D30, Aldoril D50
Methyldopa lowers blood pressure by decreasing the levels of certain chemicals in your blood. This allows your blood vessels (veins and arteries) to relax (widen) and your heart to beat more slowly and easily.
Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.
The combination of hydrochlorothiazide and methyldopa is used to treat high blood pressure (hypertension).
Hydrochlorothiazide and methyldopa may also be used for purposes not listed in this medication guide.
Before using hydrochlorothiazide and methyldopa, tell your doctor if you have kidney disease (or are on dialysis), angina pectoris (chest pain), glaucoma, asthma, gout, lupus, diabetes, an allergy to sulfa drugs or penicillin, or if you have ever had a stroke.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.
There are many other drugs that can interact with hydrochlorothiazide and methyldopa. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
liver disease (including cirrhosis or hepatitis);
a history of liver problems caused by taking methyldopa; or
if you are unable to urinate.
To make sure you can safely take hydrochlorothiazide and methyldopa, tell your doctor if you have any of these other conditions:
kidney disease (or if you are on dialysis);
angina pectoris (chest pain);
glaucoma;
asthma;
gout;
lupus;
diabetes;
an allergy to sulfa drugs or penicillin; or
if you have ever had a stroke.
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results.
Your blood pressure will need to be checked often. Your liver function may also need to be tested. Visit your doctor regularly.
Your blood and urine may both be tested if you have been vomiting or are dehydrated.
Hydrochlorothiazide can interfere with the results of a thyroid test. Tell any doctor who treats you that you are using a thiazide diuretic.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.
eye pain, vision problems;
feeling like you might pass out;
chest pain, slow heart rate, feeling short of breath, even with mild exertion;
swelling, rapid weight gain;
easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
pale or yellowed skin, dark colored urine, fever, confusion or weakness;
nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
joint pain or swelling with fever, swollen glands, muscle aches, nausea, vomiting, chest pain, unusual thoughts or behavior, and/or seizure (convulsions);
numbness, drooping, or loss of movement in one side of your face;
jerky or rolling muscle movements you cannot control;
high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss);
urinating less than usual or not at all;
fever, skin rash, bruising, severe tingling, numbness; or
severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling;severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Less serious side effects may include:
stomach cramps, diarrhea, constipation;
depressed mood, trouble concentrating;
joint pain;
muscle pain or weakness;
restless feeling;
dizziness, drowsiness, headache;
soreness or black discoloration of your tongue;
blurred vision; or
impotence, or loss of interest in sex.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all other medicines you use, especially:
cholestyramine (Prevalite, Questran);
colestipol (Colestid);
digoxin (Lanoxin);
insulin or oral diabetes medication;
lithium (Eskalith, LithoBid);
a barbiturate such as phenobarbital (Solfoton);
medicines that contain iron, such as ferrous gluconate (Fergon, Ferralet, Simron), or ferrous sulfate (Chem-Sol, Feosol, Slow Fe, and others);
muscle relaxers or narcotic pain medicine;
steroids (prednisone and others);
other blood pressure medications;
a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others.
This list is not complete and other drugs may interact with hydrochlorothiazide and methyldopa. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
See also: Aldoril5 side effects (in more detail)
tin-za-PAR-in
Epidural or spinal hematomas, which may result in long-term or permanent paralysis, may occur in patients who are anticoagulated with low molecular weight heparins or heparinoids and are receiving neuraxial anesthesia or undergoing spinal puncture. Factors that can increase the risk of developing these hematomas include: use of indwelling epidural catheters, concomitant use of drugs affecting hemostasis such as NSAIDs, platelet inhibitors, or other anticoagulants, or history of traumatic or repeated epidural or spinal puncture, spinal deformity, or spinal surgery. Monitor patients frequently for neurological impairment. If neurological compromise is noted, urgent treatment is necessary. Consider risks/benefits before neuraxial intervention in patients anticoagulated or to be anticoagulated for thromboprophylaxis .
In the U.S.
Available Dosage Forms:
Therapeutic Class: Anticoagulant
Pharmacologic Class: Low Molecular Weight Heparin
Tinzaparin is used for the treatment of deep venous thrombosis, a condition in which harmful blood clots form in the blood vessels of the legs. These blood clots can travel to the lungs and can become lodged in the blood vessels of the lungs, causing a condition called pulmonary embolism. Tinzaparin is used for several days after surgery, while you are unable to walk. It is during this time that blood clots are most likely to form. Tinzaparin also may be used for other conditions as determined by your doctor.
tinzaparin is available only with your doctor's prescription.
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For tinzaparin, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to tinzaparin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of tinzaparin in the pediatric population. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of tinzaparin in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment in the dose for patients receiving tinzaparin.
| Pregnancy Category | Explanation | |
|---|---|---|
| All Trimesters | B | Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus. |
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking tinzaparin, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using tinzaparin with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using tinzaparin with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
The presence of other medical problems may affect the use of tinzaparin. Make sure you tell your doctor if you have any other medical problems, especially:
A nurse or other trained health professional will give you tinzaparin. tinzaparin is given as a shot under your skin, usually in the abdomen.
If you are using tinzaparin at home, your doctor will teach you how to inject yourself with the medicine. Be sure to follow the directions carefully. Check with your doctor if you have any problems using the medicine.
You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems from the injections.
If the medicine in the vial (glass container) has changed color, or if you see particles in it, do not use it.
Put used syringes in a puncture-resistant, disposable container, or dispose of them as directed by your doctor.
The dose of tinzaparin will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of tinzaparin. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
Call your doctor or pharmacist for instructions.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.
It is very important that your doctor check your progress at regular visits to make sure tinzaparin is working properly. Blood tests will be needed to check for unwanted effects. Be sure to keep all appointments.
tinzaparin may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a rash; itching; swelling of the face, tongue, and throat; trouble breathing; or chest pain after you receive tinzaparin.
Make sure your doctor knows if you have had an allergic reaction to heparin, sulfites, benzyl alcohol, or pork products.
Tinzaparin may increase your chance of bleeding or bruising. This risk is higher if you have a catheter in your back for pain medicine or anesthesia (sometimes called an "epidural"), or if you have kidney problems. The risk of bleeding increases as the severity of your kidney problems increases. Check with your doctor right away if you notice any unusual bleeding or bruising; black, tarry stools; bleeding gums; blood in the urine or stools; or pinpoint red spots on your skin.
You may bleed and bruise more easily while you are using tinzaparin. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Be careful when using sharp objects, including razors and fingernail clippers. Avoid nose picking and forceful nose blowing.
Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done.
Make sure any doctor or dentist who treats you knows that you are using tinzaparin. You may need to stop using tinzaparin several days before having surgery or medical tests.
tinzaparin contains benzyl alcohol which may cause serious reactions to newborn or premature infants. Discuss this with your doctor if you are concerned.
Do not take or discontinue other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines, and herbal or vitamin supplements.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See also: tinzaparin Subcutaneous side effects (in more detail)
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